Publications

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Journal Publications

Robust, non-fouling liters-per-day flow synthesis of ultra-small catalytically active metal nanoparticles in a single-channel reactor

Wai Kuan Wong, Swee Kun Yap, Yi Chen Lim, Saif A. Khan, Frédéric Pelletier, and Elena Cristina Corbos

React. Chem. Eng., 2017, Advance Article

DOI: 10.1039/c7re00072c

Published Date (Web): 30 June 2017

Bottom-up Structural Design of Crystalline Drug-Excipient Composite Microparticles via Microfluidic Droplet-based Processing

Eunice W. Q. Yeap, Denise Z. L. Ng, Ammu Prhashanna, Ambika Somasundar, Andrew J. Acevedo, Qisong Xu, Fatma Salahioglu, Marc V. Garland, and Saif A. Khan

Cryst. Growth Des., Article ASAP

DOI: 10.1021/acs.cgd.6b01701

Published Date (Web): 21 April 2017

Three-phase microfluidic reactor networks – Design, modeling and application to scaled-out nanoparticle-catalyzed hydrogenations with online catalyst recovery and recycle

Swee Kun Yap, Wai Kuan Wong, Nicholas Xiang Yang Ng, and Saif A. Khan

Chem Eng. Sci., 2016

DOI: 10.1016/j.ces.2016.12.005

Published Date (Web): 1 December 2016

Co-micellization behavior of triblock copolymers in the presence of hydrophobic drug molecules: A simulation study

Ammu Prhashanna, Wee Kian Tan, Saif A. Khan, and Shing Bor Chen

Colloids Surf., B, 148, 299–307

DOI: 10.1016/j.colsurfb.2016.09.004

Published Date (Web): 5 September 2016

Weaving colloidal webs around droplets – Spontaneous assembly of extended colloidal networks encasing microfluidic droplet ensembles

Lu Zheng, Leon Yoon Ho, and Saif A. Khan

Soft Matter, Comm, 2016, Advance Article

DOI: 10.1039/C6SM01318J

Published Date (Web): 2 September 2016

Room Temperature Batch and Continuous Flow Synthesis of Water-Stable Covalent Organic Frameworks (COFs)

Yongwu Peng, Wai Kuan Wong, Zhigang Hu, Youdong Cheng, Daqiang Yuan, Saif A. Khan, and Dan Zhao

Chem. Mater., Article ASAP

DOI: 10.1021/acs.chemmater.6b01954

Published Date (Web): 12 July 2016

Micelle morphology and chain conformation of triblock copolymers under shear: LA-DPD study

Ammu Prhashanna, Saif A. Khan, Shing Bor Chen

Colloids Surf., A, 506, 457–466

DOI: 10.1016/j.colsurfa.2016.07.003

Published Date (Web): 5 July 2016

Coupled equivalent circuit models for fluid flow and heat transfer in large connected microchannel networks – The case of oblique fin heat exchangers

Nasi Mou, Poh Seng Lee, and Saif A. Khan

Int J. Heat Mass Tran, 102 (2016): 1056-1072

DOI: 10.1016/j.ijheatmasstransfer.2016.06.069

Published Date (Web): 20 June 2016

Droplet Microfluidics with a Nanoemulsion Continuous Phase

Tonghan Gu, Eunice W. Q. Yeap, Ambika Somasundar, Ran Chen, T. Alan Hatton, and Saif A Khan

Lab Chip, 2016, 16, 2694 – 2700

DOI: 10.1039/C6LC00601A

Published Date (Web): 10 June 2016

Investigations on the Influence of Flow Migration on Flow and Heat Transfer in Oblique Fin Microchannel Array

Nasi Mou, Yong Jiun Lee, Poh Seng Lee, Pawan K. Singh, and Saif A. Khan

J. Heat Transfer 138(10), 102403

DOI: 10.1115/1.4033540

Published Date (Web): 7 June 2016

Kinetics of Chain Exchange between Diblock Copolymer Micelles

Ammu Prhashanna, Saif A. Khan, and Shing Bor Chen

Macromolecular Theory and Simulations, 2016

DOI: 10.1002/mats.201600016

Published Date (Web): 28 April 2016

Prediction of the shape and pressure drop of Taylor bubbles in circular tubes

Aditya Cherukumudi, Evert Klaseboer, Saif A. Khan, and Rogerio Manica

Microfluid Nanofluid (2015) 19:1221–1233

DOI: 10.1115/1.4033540

Published Date (Web): 09 September 2015

Co-Micellization Behavior in Poloxamers: Dissipative Particle Dynamics Study

Ammu Prhashanna, Saif A. Khan, and Shing Bor Chen

The Journal of Physical Chemistry B, 2015, 119 (2), pp 572–582

DOI: 10.1021/jp509237r

Published Date (Web): 18 December 2014

Microfluidic Fabrication of Multi-Drug-Loaded Polymeric Microparticles for Topical Glaucoma Therapy

Reno A. L. Leon, Ambika Somasundar, Abu Zayed M. Badruddoza, and Saif A. Khan

Part. Part. Syst. Charact. 2015, 32, 567–572

DOI: 10.1002/ppsc.201400229

Published Date (Web): 17 December 2014

Triphasic Segmented Flow Millireactors for Rapid Nanoparticle-Catalyzed Gas–Liquid Reactions — Hydrodynamic Studies and Reactor Modeling

Swee Kun Yap, Yuan Yuan, Lu Zheng, Wai Kuan Wong, Ning Yan, and Saif A. Khan

Journal of Flow Chemistry, Volume 4, Number 4/December 2014, Pages 200-205

DOI: 10.1556/JFC-D-14-00031

Published Date (Web): 10 December 2014

Highly Selective, Kinetically Driven Polymorphic Selection in Microfluidic Emulsion-Based Crystallization and Formulation

Reno A. L. Leon, Abu Zayed M. Badruddoza, Lu Zheng, Eunice W. Q. Yeap, Arpad I. Toldy, Kay Yan Wong, T. Alan Hatton, and Saif A. Khan

Cryst. Growth Des., 2015, 15 (1), pp 212–218

DOI: 10.1021/cg501222n

Published Date (Web): 24 November 2014

Rapid nanoparticle-catalyzed hydrogenations in triphasic millireactors with facile catalyst recovery

Swee Kun Yap, Yuan Yuan, Lu Zheng, Wai Kuan Wong, Jiaguang Zhang, Ning Yan, and Saif A. Khan

Green Chemistry, Green Chem., 2014,16, 4654-4658

DOI: 10.1039/C4GC01504E

Published Date (Web): 03 September 2014

Dynamics and morphological outcomes in thin-film spherical crystallization of glycine from microfluidic emulsions–experimental studies and modeling

Arpad I. Toldy, Lu Zheng, Abu Zayed Md. Badruddoza, T. Alan Hatton, and Saif A. Khan

Cryst. Growth Des., 2014, 14 (7), pp 3485–3492

DOI: 10.1021/cg5004337

Published Date (Web): 05 June 2014

Three-dimensional parallelization of microfluidic droplet generators for a litre per hour volume production of single emulsions

D. Conchouso, D. Castro, Saif A. Khan, and I. G. Fouldsac

Lab On a Chip, 2014, Issue 14, pp 3011-3020

DOI: 10.1039/C4LC00379A

Published Date (Web): 27 May 2014

Dual-Stage Continuous-Flow Seedless Microfluidic Synthesis of Anisotropic Gold Nanocrystals

Suhanya Duraiswamy, and Saif A. Khan

Particle & Particle Systems Characterization, Volume 31, Issue 4, pages 429–432, April 2014

DOI: 10.1002/ppsc.201300266

Published Date (Web): 21 Oct 2013

Simultaneous spherical crystallization and co-formulation of drug(s) and excipient from microfluidic double emulsions

Reno A.L. Leon , Wai Yew Wan , Abu Zayed M Badruddoza , T. Alan Hatton , and Saif A. Khan

Cryst. Growth Des., 2014, 14 (1), pg 140–146

DOI: 10.1021/cg4012982

Published Date (Web): 25 November 2013

Bistability in droplet traffic at asymmetric microfluidic junctions

Pravien Parthiban and Saif A. Khan

Biomicrofluidics 7, 044123 (2013)

DOI: 10.1063/1.4819276

Published Date (Web): 23 August 2013

Monodisperse Polymeric Ionic Liquid Microgel Beads with Multiple Chemically Switchable Functionalities

Md. Taifur Rahman, Zahra Barikbin, Abu Zayed M. Badruddoza, Patrick S. Doyle, and Saif A. Khan

Langmuir, 2013, 29 (30), pp 9535–9543

DOI: 10.1021/la401613w

Publication Date (Web): 27 June 2013

Functionalized Silica Nanoparticles as Additives for Polymorphic Control in Emulsion-Based Crystallization of Glycine

Abu Zayed Md. Badruddoza, Arpad I. Toldy, T. Alan Hatton, and Saif A. Khan

Cryst. Growth Des., 2013, 13 (6), pp 2455–2461

DOI: 10.1021/cg400157y

Publication Date (Web): 12 April 2013

Dynamically tunable nanoparticle engineering enabled by short contact-time microfluidic synthesis with a reactive gas

Md. Taifur Rahman, Prasanna Ganesan Krishnamurthy, Pravien Parthiban, Abhinav Jain, Chan Pil Park, Dongpyo Kim and Saif A. Khan

RSC Adv., 2013,3, 2897-2900

DOI: 10.1039/C2RA23216B

Publication Date (Web): 21 Dec 2012

Inkjet Printing and Release of Monodisperse Liquid Crystal Droplets from Solid Surfaces

Vera Joanne Aliño , Kun Xiang Tay , Saif A. Khan , and Kun-Lin Yang

Langmuir, 2012, 28 (41), pp 14540–14546

DOI: 10.1021/la3028463

Publication Date (Web): 19 Sept 2012

Spherical Crystallization of Glycine from Monodisperse Microfluidic Emulsions

Arpad I. Toldy, Abu Zayed M. Badruddoza, Lu Zheng, T. Alan Hatton, Rudiyanto Gunawan, Raj Rajagopalan, and Saif A. Khan

Cryst. Growth Des., 2012, 12 (8), pp 3977 – 3982

DOI: 10.1021/cg300413s

Publication Date (Web): 02 Jul 2012

Fireflies-On-A-Chip: (Ionic Liquid)-Aqueous Microdroplets for Biphasic Chemical Analysis

Zahra Barikbin, Md. Taifur Rahman, and Saif A. Khan

Small, 2012

DOI: 10.1002/smll.201102748

Publication Date (Web): 19 Apr 2012

Controlling bubbles using bubbles—microfluidic synthesis of ultra-small gold nanocrystals with gas-evolving reducing agents

Saif A. Khan and Suhanya Duraiswamy

Lab Chip, 2012,12, 1807 – 1812

DOI: 10.1039/C2LC21198J

Publication Date (Web): 06 Mar 2012

Filtering microfluidic bubble trains at a symmetric junction

Pravien Parthiban and Saif A. Khan

Lab Chip, 2012,12, 582 – 588

DOI: 10.1039/C1LC20639G

Publication Date (Web): 03 Nov 2011

Hierarchical materials synthesis at soft all-aqueous interfaces

Su Hui Sophia Lee , M. K. Dawood , W. K. Choi , T. Alan Hatton and Saif A. Khan

Soft Matter, 2012, 8, 3924 – 3928

DOI: 10.1039/C2SM07373K

Publication Date (Web): 28 Feb 2012

Tunable spatial heterogeneity in structure and composition within aqueous microfluidic droplets

Su Hui Sophia Lee, Pengzhi Wang, Swee Kun Yap, T. Alan Hatton, and Saif A. Khan

Biomicrofluidics 6, 022005 (2012)

DOI: 10.1063/1.3694841

Publication Date (Web): 6 April 2012

Preface to Special Topic: Multiphase Microfluidics

Saif A. Khan

Biomicrofluidics 6, 021901 (2012)

DOI: 10.1063/1.4707391

Publication Date (Web): 24 April 2012

Modulation of surface wettability of superhydrophobic substrates using Si nanowire arrays and capillary-force-induced nanocohesion

M. K. Dawood , H. Zheng , N. A. Kurniawan , K. C. Leong , Y. L. Foo , R. Rajagopalan , S. A. Khan and W. K. Choi

Soft Matter, 8, 3549-3557

DOI: 10.1039/C2SM07279C

Publication Date (Web): 14 Feb 2012

Mimicking Both Petal and Lotus Effects on a Single Silicon Substrate by Tuning the Wettability of Nanostructured Surfaces

Dawood, M. K., Zheng, H., Liew, T. H., Leong, K. C., Foo, Y. L., Rajagopalan, R., Khan, S. A. and Choi, W.K.

Langmuir, 27 (7), 4126–4133

DOI: 10.1021/la1050783

Publication Date (Web): February 28, 2011

Microfluidic continuous magnetophoretic protein separation using nanoparticle aggregates

Su Hui Sophia Lee, T. Alan Hatton and Saif A. Khan

Microfluidics and Nanofluidics, 2011, 11, 429 – 438

DOI: 10.1007/s10404-011-0808-3

Publication Date (Web): 27 May 2011

Plasmonic Nanoshell Synthesis in Microfluidic Composite Foams

Suhanya Duraiswamy and Saif A. Khan

Nano Lett., 2010, 10 (9), 3757 – 3763

DOI: 10.1021/nl102478q

Publication Date (Web): August 23, 2010

Ionic liquid-based compound droplet microfluidics for ‘on-drop’ separations and sensing

Zahra Barikbin , Md. Taifur Rahman , Pravien Parthiban , Anandkumar S. Rane , Vaibhav Jain , Suhanya Duraiswamy , S. H. Sophia Lee and Saif A. Khan

Lab Chip, 2010, 10, 2458 – 2463

DOI: 10.1039/C004853D

Publication Date (Web): 10 Aug 2010

UV-Defined Flat PDMS Stamps Suitable for Microcontact Printing

Chang-Ying Xue, Shi Yao Chin, Saif A. Khan and Kun-Lin Yang

Langmuir 2010, 26 (5), pp 3739–3743

DOI: 10.1021/la902995j

Publication Date (Web): 7 Oct 2009

Droplet-Based Microfluidic Synthesis of Anisotropic Metal Nanocrystals

Suhanya Duraiswamy, Saif A. Khan

small 2009, 5, No. 24, 2828 – 2834

DOI: 10.1002/smll.200901453

Publication Date (Web): 28 Sep 2009

Exploring Optical Properties of Liquid Crystals for Developing Label-Free and High-Throughput Microfluidic Immunoassays

Chang-Ying Xue, Saif A. Khan, Kun-Lin Yang

Advanced Materials 2009, 21, 198-202

DOI: 10.1002/adma.200801803

Publication Date (Web): 4 Nov 2008

Microfluidic Emulsions with Dynamic Compound Drops

Saif A. Khan and Suhanya Duraiswamy

Lab Chip, 2009, 9, 1840 – 1842

DOI: 10.1039/B904119B

Publication Date (Web): 22 May 2009

Microfluidic synthesis of titania shells on colloidal silica’, Advanced Materials

S.A. Khan, K.F. Jensen

Advanced Materials 2007, 18(9), 2556-2560

DOI: 10.1002/adma.200700127

Publication Date (Web): 14 Aug 2007

Measurement of residence time distribution in microfluidic systems

Franz Trachsel, Axel Gunther, Saif Khan, Klavs F. Jensen

Chemical Engineering Science 2005, 60, 5729-5737

DOI: 10.1016/j.ces.2005.04.039

Publication Date (Web): 05 July 2005

Microfluidic Synthesis of Colloidal Silica

Khan, S. A., Günther, A., Schmidt, M. A. and Jensen, K. F.

Langmuir 2004, 20 (20), pp 8604–8611

DOI: 10.1021/la0499012

Publication Date (Web): September 3, 2004

Transport and reaction in microscale segmented gas–liquid flow

Axel Günther , Saif A. Khan , Martina Thalmann , Franz Trachsel and Klavs F. Jensen

Lab Chip, 2004, 4, 278-286

DOI: 10.1039/B403982C

First published on the web 16 Jun 2004

Patents Held/Applied

Rapid Nanoparticle-Catalyzed Hydrogenations In Triphasic Segmented Flow Millireactors With Facile Catalyst Recovery

Yap, S. K., Yuan, Y., Yan, N. and Khan, S. A. (2014)

US Provisional Application No. 62/014,742

Manufacture of A Pharmaceutical Product

Leon, R. A. L., Wan, W. Y., Badruddoza, A. Z. M., Hatton, T. A. and Khan, S. A. (2014)

International Patent Application No: PCT/SG2014/000486

A Method Of Synthesizing Colloidal Nanoparticles

Khan, S. A. and Duraiswamy, S. (2014)

US Patent Application No: 13/040,860

A passive microfluidic device and a method of forming the same

Ng, S. C., Liow, S. L., Chen, N., Tong, Y. W., Khan, S. A. and Fang, B. S. (2013)

WIPO Patent No.: WO 2013/115725 A1

Process For Altering Wetting Properties of A Substrate Surface

Choi, W. K., Dawood, M. K., Khan, S. A. and Rajagopalan, R. (2011)

International patent application: PCT/SG2011/000312

Bioassay using liquid crystal

Yang, K. L., C. Y. Xue, S. A. Khan and X. Bi (2010)

International patent: WO2010/042070A1

Microchemical method and apparatus for synthesis and coating of colloidal nanoparticles

Khan, S. A. and Jensen, K. F. (2005)

US Patent Application No: 10/626,436

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